Treatment
1. Surgical treatment
Surgical treatment remains the main treatment for breast cancer, one of the means. There are many surgical, its selection is still lacking a unified opinion, the general trend is to minimize the surgical damage to the device under the right conditions allow try to breast-conserving therapy in patients with early breast cancer appearance. No matter what kind of surgical use, must be strictly controlled in order to cure the main function and appearance retention, supplemented by principle.
(A) The first surgical indications Halsted radical mastectomy, because surgery is reasonable, effective clear, the past century become the treatment of breast cancer followed a standard way. Nearly half a century, breast cancer surgery and conducted a number of exploratory changes, the general trend of no more than the expansion of both conservative and is still debated. Partial breast resection and mastectomy is the representation of conservative surgical procedure. Be supplemented by postoperative radiotherapy, radiation dose varies, generally 30 ~ 70Gy, the limitations of the strict selection of early cancer, can receive a better effect. But whether as a routine treatment for early breast cancer, and how to choose the accuracy of such early cancers would be difficult to reach a conclusion.
(B) surgical contraindications
1. Systemic contraindications: â‘  tumor distant metastasis. â‘¡ elderly and the infirm who can not tolerate surgery. â‘¢ generally poor, those who showed cachexia. â‘£ important organ dysfunction can not tolerate surgery.
2. Localized lesions contraindications: Ⅲ patients with one of the following conditions: ① the breast skin, orange peel-like swelling of more than half of the breast area; ② the breast skin and the advent of satellite-like nodules; ③ breast violation of the chest wall; ④ clinical examination sternum lymph node enlargement and confirmed to be transferred; ⑤ ipsilateral upper extremity edema; ⑥ supraclavicular lymph nodes confirmed by pathology for the transfer; ⑦ inflammatory breast cancer. Both of the following five situations: ① tumor ulceration; ② the breast skin and orange peel-like swelling of the entire breast area of l / 3 or less; ② carcinoma with pectoralis major fixed; ④ maximum length axillary lymph node diameter of more than 2.5cm; ⑤ adhesion to each other or with axillary lymph node skin, deep tissue adhesion.
(C) surgical method
1. Radical mastectomy: in 1894, and Meger, respectively Halsted radical mastectomy operation method on the surgical principles: â‘  the primary tumor and regional lymph nodes should be en bloc resection; â‘¡ removed all the breast and chest large and small muscles; â‘¢ axillary for complete removal of lymph nodes en bloc. Haagensen improved radical surgery of breast cancer, emphasizing the operative should be particularly thorough and meticulous dissection flap mainly â‘ ; â‘¡ flap completely separated from the chest wall chest will be large and small muscles cut out reveal; â‘¢ axillary dissection , chest Nagakami diameter should be retained, such as the axillary lymph nodes had no significant while those thoracodorsal nerve can also be retained; â‘£ chest wall defect to be all skin grafting. Intraoperative complications are: â‘  axillary vein injury: multi-axillary vein due to the anatomy of the surrounding fat and lymph tissue, the anatomy is unclear, or the axillary vein due to cut off the branch, the result too close to the axillary vein. Therefore, a clear exposure and to retain the branch stump, is important. â‘¡ pneumothorax: In the cut pectoralis major, pectoralis minor muscle in the ribs just end, sometimes because of the small blood vessels clamp chest wall perforating branches, the next clamp too deep an extent which rendered touch-breaking intercostal muscle and pleura, resulting in tension pneumothorax. Postoperative complications included: â‘  subcutaneous fluid: Multi-skin graft fixation because of poor or poor drainage due. The skin and chest wall can be used multiple suture between the organization and sustained negative pressure drainage and prevention. â‘¡ skin necrosis: skin suture too tight and the skin thinner and so can their causes. Large skin defect, the appropriate use of skin grafting. â‘¢ ipsilateral upper extremity edema. Ipsilateral upper extremity flattering limited: mainly postoperative reduction in activity, skin scarring caused by traction. Accordingly, I request an early postoperative functional exercise should normally be a month or so after the basic level can be achieved flattering ease.
2. Breast cancer, extended radical surgery: breast cancer, extended radical surgery, including breast cancer, radical mastectomy or radical mastectomy and internal mammary lymph node dissection, that is, clear the 1-4 intercostal lymph nodes, the time required to remove the second, third and fourth costal cartilage. Surgical methods are within the law and pleural pleural outside France, the former major trauma, complications and more and they tend to use the latter.
3. Imitation radical mastectomy (modified radical mastectomy): mainly used for non-invasive cancer or invasive cancer, Phase I. Phase â…¡ clinical no obvious axillary lymph nodes who may choose to apply.
(1) â…  Type: Retention pectoralis major, pectoralis minor muscle. Principle of separation of the skin incision and skin flap with radical mastectomy. Do first mastectomy (surgical fascia together with removal of pectoralis major muscle), will the whole milk to the axillary dissection side, and then OK axillary lymph node dissection, removing the basic scope of the same radical mastectomy. God chest diameter should be retained. Finally, the whole milk and axillary lymph tissue en bloc.
(2) â…¡ type: Retention pectoralis major, pectoralis minor muscle resection. Steps such as the skin incision with the former, the outer edge of the breast after dissociation to the pectoralis major, pectoralis major muscle to cut off the first rib attachment points 4,5,6, and turned to the top of the to expand the surgical field, in the Department of scapula coracoid pectoralis minor cut muscle attachment points, the following steps with the radical surgery, but reservations should be noted that the chest nerves and accompanying vessels, and eventually the whole breast, chest muscles and underarm lymph tissue of small en bloc resection.
4. Breast surgery alone: As an old-style operation which had been replaced by radical mastectomy. In recent years, along with the development of breast cancer biology, while the mastectomy renewed attention. Its indications: First, non-invasive or axillary lymph node metastasis of early cases, postoperative radiotherapy could not. 2 is a partial view of breast cancer with late postoperative radiotherapy alone. From the ever-growing demand to see the beauty school, full-mastectomy breast reconstruction is still required complex surgery. Would be unsuitable for young women in the early disease. The main indications so it should be limited to old and feeble person or some only palliative resection in advanced cases.
5. Less than the surgical removal of the whole milk: In recent years, due to advances in radiotherapy equipment and found that the lesions than in the past for the early and the patient’s quality of life after surgery has higher expectations and therefore reported that there were a lot less than the whole conservative mastectomy surgery. Since the partial removal of surgical approach until the l / 4 mastectomy and postoperative radiotherapy for some applications.
Breast-conserving surgery is not suitable for all breast cancer cases, and could not replace all of the radical operation, but an improved breast cancer treatment method should be taken to avoid recurrence. The indications as follows: ① tumors less suitable for clinical T1 and some T2 (less than 4 cm) following lesions; ② around the tumor, located in often inappropriate for those under the areola; ③ solitary lesion; ④ well-demarcated tumor , such as the naked eye or under a microscope, the borders are often not see clearly inappropriate; ⑤ axillary lymph node metastasis with no clearly defined. The effects of treatment with the following factors: ① tumor resection margin must have a normal border, if there is sufficient margin of normal organizers a better prognosis; ② primary tumor size and histological grade; ③ postoperative radiotherapy after operation If no radiation therapy, local recurrence is higher.
2. Radiation Therapy
Radiation therapy is a major component of treatment for breast cancer is one of the means of local treatment. Compared with the surgical treatment are less prone to anatomy, patients with physical limitations and other factors, but the effects of radiation therapy is being affected by the impact of the biological effects of radiation. Commonly used in radiotherapy facilities, with the current more difficult to achieve “full kill” the purpose of tumors, the effect worse than the surgery. Therefore, at present most scholars do not advocate the right line of incurable breast cancer radiotherapy alone. Radiation therapy used for comprehensive treatment, including radical surgery, either before or made after adjuvant therapy, palliative treatment of advanced breast cancer. Over the past 10 years, the earlier breast cancer with partial excision of the comprehensive treatment of increasing efficacy and no significant difference between radical surgery, radiotherapy, surgery in the narrow range plays an important role.
(A) Preoperative radiotherapy
1. Indications
(1) The primary foci larger, it is estimated there are those in the direct operation.
(2) tumor growth and rapid, significant growth in the short term those.
(3) The original skin lesion marked edema, or chest adhesions were.
(4) axillary lymph nodes or with large skin and surrounding tissues were significant adhesions.
(5) Application of preoperative chemotherapy shrink tumors unsatisfactory cases.
(6) to seek surgical resection in patients with inflammatory breast cancer.
2. The role of preoperative radiotherapy
(1) can increase the rate of surgical resection, so that part of the inoperable patients the opportunity to re-operation.
(2) Since the radiation inhibit tumor cell viability, can reduce the recurrence rate and metastasis rate, thereby enhancing the survival rate.
(3) Due to radiation, prolonged preoperative observation period, there have been making some subclinical cases of distant metastasis to avoid an unnecessary surgery.
3. The shortcomings of preoperative radiotherapy
Increase in complications affecting the postoperative stage and hormone receptor determination of the right.
4. The application of methods of preoperative radiotherapy
Preoperative radiotherapy should be as far as possible high-energy rays can better protect the normal tissue and reduce complications. Radiologic technology, at present the majority of conventional segmentation, medium-dose. Generally do not have rapid radiation or hyperfractionated radiotherapy. Radiation 4 to 6 weeks after the end of an operation is more desirable.
(B) postoperative radiotherapy
The need for radical surgery radiation treatment of breast cancer was once the most contentious issues. In recent years, more authors acknowledge postoperative radiotherapy can reduce local, regional recurrence rate. Since the Fishor put forward a new view of breast cancer after the treatment of breast cancer has gradually shifted from the local treatment of combined treatment. Widely used in adjuvant chemotherapy and postoperative radiotherapy after radical resection is no longer as a routine treatment, but rather selectively applied.
1. Indications
(1) simple mastectomy.
(2), radical surgery with axillary in the pathology report on the group or group of axillary lymph node metastasis.
(3) confirmed by pathology after radical resection of metastatic lymph nodes accounted for more than half the total number of lymph nodes examined or have four or more lymph node metastasis.
(4) pathologically confirmed cases of internal mammary lymph node metastasis (irradiated supraclavicular area).
(5) The primary breast lesion is located in the central or medial bidder as radical surgery, in particular, with axillary lymph node metastasis.
2. Radiotherapy principles
(1) â… , â…¡ stage breast cancer after radical surgery or radical imitation, outside the primary tumor in the breast quadrant, axillary lymph node-negative pathological examination, postoperative radiotherapy did not; axillary lymph node-positive, the postoperative irradiation in breast area and clavicle the upper and lower areas; the primary tumor in the breast area or in the central quadrant, axillary lymph node negative, pathological examination and postoperative irradiation only the internal mammary area, axillary lymph node-positive, the increase up and down according to the subclavian area.
(2) â…¢ period of radical mastectomy, regardless of axillary lymph node-positive or negative, all radiation levels inside the breast area and collarbone area. According to the number of the number of positive axillary lymph nodes and chest wall involvement, they may also take into account with or without chest wall irradiation.
(3) mastectomy, axillary lymph nodes have been removed, and no further exposure to the armpit area, unless the surgical removal of residual lesions are not completely or only when it considered the armpit area of additional exposure.
(4) radiotherapy useful to 4 ~ 6 weeks after surgery to begin, there is skin grafting may be extended for 8 weeks.
(C) radiation therapy-based treatment
In the past for locally advanced tumors, non-surgical indications for radiation therapy are often palliative in nature. In recent years, with the radiation equipment and technology to improve and enhance, as well as the progress of radiation biology, radiation can receive a higher dose of local tumor and surrounding normal tissue damage less, treatment has improved significantly. At present, began minor surgery plus radiation therapy for early breast cancer research, so that radiation therapy in the treatment of breast cancer, radical shift from palliative. Most authors believe that the original lesion less than 3cm, N0 or N1 patients who could be considered minor surgery and radiotherapy. For locally advanced breast cancer, radiotherapy is still an effective local treatment, radiation anterior resection of all tumor or for a simple mastectomy can improve efficacy.
(D) of recurrence and metastasis of radiation therapy
Postoperative recurrence of breast cancer is a bad sign, but not hopeless.
The appropriate local treatment can improve the quality of life and prolong survival. Irradiation, the Ono Ono radiation exposure than the good curative effect, it should maximize the use of irradiation Ohno. For the recurrent cases, should be used for radiation, chemotherapy, combined therapy, especially for the rapid development of relapse. Distant metastasis of breast cancer occurs when the first consideration chemotherapy, and radiotherapy may be appropriate to relieve symptoms, reduce the suffering of the patient. Such as bone metastases patients who were pain after radiotherapy reduce or disappear. For thoracic and lumbar spine metastasis patients, radiation can prevent or delay the occurrence of paraplegia.
3. Hormone receptor determination and the relationship between endocrine therapy
Hormone receptor determination and a clear relationship between the efficacy of breast cancer: â‘  Application of estrogen receptor-positive endocrine therapy response rate was 50% ~ 60%, while the negative efficiency below 10%. Simultaneous Determination of progesterone receptor may be more accurately estimate the effect of endocrine therapy, both positive and efficient up to more than 77%. Receptor content and effect relationship is a positive correlation, the higher the content of the treatment effect was not better. â‘¡ receptor-negative cells are often poorly differentiated. Receptor-negative patients tend to have a recurrence after operation. Regardless of lymph node metastasis, receptor-negative than positive worse prognosis. Positive recurrence is often preferred if the skin, soft tissue or bone metastases, while the negative ones tend to visceral metastasis. â‘¢ the determination of hormone receptors is currently used to develop postoperative adjuvant therapy program, the receptor-positive patients, especially post-menopausal hormonal therapy can be applied as a postoperative adjuvant therapy. The pre-menopausal or hormone receptor-negative may lead to adjuvant chemotherapy based.
4. Endocrine therapy
Endocrine therapy for breast cancer, non-curative, but for hormone-dependent breast cancer, but it can receive different levels of palliative effect. The cytoplasm and nuclei of cancer cells within the estrogen receptor (ER) content of more of its hormone-dependent are also stronger. And should bear in mind that breast cancer occurred before menopause and amenorrhea occurred after a difference in the treatment of breast cancer.
(A) pre-menopausal (or amenorrhea after one year) treatment of patients with
1. Androgen deprivation therapy
Including surgery and radiation castration castration. The former is better for the body, entry into force of those who need hormonal therapy; the latter for the general condition is poor, difficult to tolerate surgery. Without the application of selected cases of ovarian resection rate was 30% ~ 40%, while the hormone receptor-positive cases were effective up to 50% ~ 60%. Preventive removal of ovaries is currently mainly used in pre-menopausal (especially 45 to 50 years) more extensive lymph node metastasis in patients at high risk of recurrence, while determination of hormone receptor-positive, cases of post-menopausal or younger are not suitable for preventive removal of ovaries .
2. Endocrine therapy
(1), testosterone propionate: 100mg, intramuscularly, daily one time, used in conjunction five times, was reduced to three times a week, depending on the situation and to alleviate symptoms of systemic reactions can be used reduction, sustained 4 months or so. Such as the medication 6 weeks invalid, can be disabled.
(2) fluorine Oxymesterone: the testosterone propionate similar, but the role of male hormones is relatively small. For oral dose 10 ~ 30mg / day. The drug sub-2mg, 5mg and 10mg three kinds of dosage forms.
(3) dimethyl testosterone: testosterone derivatives, the role of testosterone propionate stronger than the 2.5 times, for oral, 150 ~ 300mg / day.
(B) post-menopausal (amenorrhea more than 1 year) treatment of patients can use either of the following drugs.
1. Tamoxifen (TAM): an anti-estrogen drug that works with the cancer cells of estrogen receptors, inhibit cancer cell proliferation. Commonly used dose of 10mg, oral, 2 times / day. An additional dose not improve efficacy. The main side effects are: ① gastrointestinal reactions: loss of appetite, nausea, vomiting and diarrhea to individual; ② reproductive system: amenorrhea, vaginal bleeding, genital itching; ③ neuropsychiatric symptoms: headache, dizziness, depression; ④ skin: facial flushing, skin rash; ⑤ hemogram: occasional white blood cells and thrombocytopenia, the blood used with caution, as the lower; ⑥ individual patients abnormal liver function; ⑦ affect the fetus, pregnancy, lactation hanged. ⑧ right retina there was damage, can affect vision.
2. Ammonia Glutethimide: 125mg, orally, 4 times / day, while oral administration of hydrocortisone 25mg, 2 times / day, or strong pine 5mg, 2 times / day. After a week of ammonia Glutethimide increments to 250mg, 2 times / day, hydrocortisone 25mg, 4 times / day, or strong pine 5mg, 3 times / day.
3. Medroxyprogesterone acetate 200 ~ 300mg intramuscularly, 2 times / day.
4. Diethylstilbestrol 1 ~ 2mg, orally, 3 times / day.
5. Ethinylestradiol (ethinylestradiol) This product is synthetic estrogen, vitality strong 0.5 ~ 1mg, oral, 3 times / day.
5. Chemotherapy
(A) the principle of the majority of adjuvant chemotherapy for breast cancer is a systemic disease has been a large number of experimental studies and confirmed by clinical observation. When the breast cancer grown to more than lcm, clinically palpable mass, often it is systemic disease, distant micrometastasis can exist only with the current inspection methods not yet discovered. The purpose of surgery is to make the primary tumor and regional lymph nodes are the greatest degree of local control and reduce local recurrence and improve survival rate. However, after tumor removal, the body still exist remnants of tumor cells. Based on the time of diagnosis of breast cancer is the concept of a systemic disease, systemic chemotherapy is aimed at the eradication of residual tumor cells in the body to improve the surgical cure rate.
(B) neoadjuvant chemotherapy
1. The significance of preoperative chemotherapy
(1) early control of micro-metastasis.
(2) to enable the primary tumor and its surrounding the proliferation of cancer cells or in part, by the degeneration of kill in order to reduce postoperative recurrence and metastasis.
(3) in advanced breast cancer, and inflammatory breast cancer limits the implementation of surgical treatment. Preoperative chemotherapy can shrink tumors in order to surgical resection.
(4) The removal of the tumor samples based on evaluation of effects of preoperative chemotherapy, as surgery or recurrence of reference for the selection of chemotherapy regimens.
2. The method of preoperative chemotherapy
(1) preoperative chemotherapy: Shanghai Medical University Cancer Hospital since 1978, pairs of 96 cases of breast cancer patients before oral administration of benzene, pyrimidine mustard, daily 15mg, clothes ld stop 2d, taking the total of 45mg after surgery. Compared with the control group, 94 cases, â…¢ period of 5-year survival rate of patients in the treatment group was 56.3% in control group 39.3%.
(2), preoperative intra-arterial infusion chemotherapy: There thoracic artery and the subclavian artery in two ways.
(C) adjuvant chemotherapy
1. The indications for postoperative adjuvant chemotherapy
(1) axillary lymph node-positive pre-menopausal women, regardless of how estrogen receptors are already required to use combined chemotherapy should be used as a standard treatment program.
(2) axillary lymph node-positive and estrogen receptor-positive postmenopausal women, it should be the preferred anti-estrogen therapy.
(3) axillary lymph node-positive and estrogen receptor-negative post-menopausal women, chemotherapy can be considered, but not recommended as a standard program.
(4) axillary lymph node-negative pre-menopausal women do not generally recommend adjuvant therapy, but some high-risk patients should consider adjuvant chemotherapy.
(5), axillary lymph node-negative postmenopausal women, regardless of their level of estrogen receptors, without adjuvant chemotherapy for the indication, but some high-risk patients should be considered adjuvant chemotherapy.
The high-risk node-negative breast recurrence factors are the following points: â‘  estrogen receptor (ER, PR)-negative. â‘¡ a high percentage of tumor cells in S phase. â‘¢ aneuploid tumors. â‘£ CerbB-2 oncogene overexpression or amplification of those who have.
2. For the modern view of Adjuvant Chemotherapy
(1) The early use of postoperative adjuvant chemotherapy should strive for in the 2 weeks after application, no later than one month after, if the lesion to be obvious after use, will reduce the effect.
(2) adjuvant chemotherapy in combination chemotherapy compared with single-agent chemotherapy for good.
(3) adjuvant chemotherapy to achieve a certain dose, to achieve the planned dose of 85% effective.
(4) The treatment period should not be too long, advocates of breast cancer after 6 consecutive cycles of chemotherapy.
3. Recommended regimen
(1) CMF program: It is a classic program of breast cancer chemotherapy
Cyclophosphamide (CTX) 400mg/m2 intravenous d1d8
Methotrexate (MTX) 200mg/m2 intramuscular d1d8
Fluorouracil (5-Fu) 400mg/m2 intravenous infusion of dl-5
Repeated every three weeks
(2) CAF Program
Cyclophosphamide (CTX) 400mg/m2 intravenous d1d8
Adriamycin (ADM) 300m8/m2 intravenous d1
Fluorouracil (5-Fu) 400mg/m2 infusion d1-s
Repeated every three weeks
(3) Cooper Program
Cyclophosphamide daily 2.5mg/kg, oral
Methotrexate weekly 0.7mg/kg, intravenous injection used in conjunction for 8 weeks.
5 – fluorouracil weekly 12mg/kg, intravenous injection, after a meeting every other week
New alkaline Changchun used in conjunction 34mg/kg per week 4 to 5 weeks.
Strong pine daily 0.75mg/kg, after l / 2 volume, together with the 10d, 5mg / d used in conjunction 3 weeks
4. Breast cancer second-line chemotherapy
(1) CEF Program
D1d8 intravenous cyclophosphamide 500g/m2
Epirubicin 50mg/m2 intravenously d1
5 – fluorouracil 500mg/m2 intravenous d1-3;
(2) DCF program
M due anthraquinone 10mg/m2 intravenously dl
Cyclophosphamide 500mg/m2 intravenous d1
5 – fluorouracil looomg/m2 intravenous d1
(D) of bone metastases chemotherapy combined with chemotherapy on the brain, liver, lung and other soft-tissue transfer of bone metastases than good results. But there are also
Reported using a powerful combination chemotherapy to bone metastasis foci disappeared completely. Guanghui ADM (MTH) suppress the lytic effect clinically for the treatment of osteolytic destruction of bone metastasis caused by hypercalcemia. Frequently used programs: AMO program: Adriamycin (ADM) 40mg/m2 intravenous injection, the first l, 8 days; Changchun, a new alkaline 1.4mg/m2, intravenous injection, the first 1,8 days; brilliant ADM (MTH) 2mg soluble 200m15% glucose solution, 2 hours drops End, the first l, 8,15,22 days; every 28 days for a course of treatment, a total of three treatments. Limitations of the disease, could tie in with radiotherapy.
(E) the transfer of the central nervous system, chemotherapy
1. Without cerebral edema, may be the first x-ray tomography positioning, given radiotherapy. In patients with cerebral edema, mannitol and diuretics should be the first to use high-dose corticosteroids control of cerebral edema.
2. Lesions or can not locate a wide range, it can easily through the blood-brain barrier with the first fat-soluble chemotherapeutic drugs, such as CCNU oral 100mg every 3-4 weeks one time, MECCNul25mg orally every 4 to 6 weeks one time.
(Vi) chemotherapy for malignant pleural effusion pleural effusion try to draw the net, and then use the following chemotherapeutic agents into the thoracic cavity: ① Xiaoliu mustard 40 ~ 60mg; ② mustard 10mg; ⑦ Thio-Tepa 30mg; ④ mitomycin 6 ~ 8mg ; ⑤ fluorouracil looomg; ⑥ cis-chloride platinum 90 ~ 120mg. More chemotherapy drugs, in addition to cis-platinum chloride injection every 3 weeks for a meeting (and body hydration), the general intrapleural injection of 1 times per week.
6. Chinese medicine therapy
(1) Chinese medicine treatment principles:
â‘  combat poison with poison Law: ancient physicians to treat cancer drugs, mainly most of them have attacked the use of the effectiveness of its open-knot Sida, the gradual elimination of residual cancer cells, but clinical must be carefully managed, Enough is enough.
â‘¡ Qingrejiedu law: in the heat antidote, there are many anti-cancer traditional Chinese medicine. Qingrejiedu method is to treat malignant tumors, one of the most commonly used rules. In the middle and advanced breast cancer patients, more commonly associated with toxic hot hot Ecchymosis intrinsic right or wrong, the symptoms, this time in this Dafa can be combined with other methods, treatment, multi-effect was good.
â‘¢ blood circulation Method: Chinese medicine experts believe that the tumor and blood stasis, blood stasis is one of the causes of breast cancer pathology. Blood circulation medicine applications, not only can improve breast cancer patients, “hypercoagulable state” so that cancer cells in the anti-cancer drugs and the patient’s own immune cells under suppression, but also reduces platelet aggregation, reduction of tumor metastasis is conducive to foci of cancer control and removal.
â‘£ rousing Law: Chinese medicine believes that when the body upright deficiency, the evil to the Cou that the causative agent can play a role, which led to the occurrence of breast cancer and make cancer to invasion, proliferation and metastasis, so rousing the treatment of breast cancer, one of the fundamental methods.
⑤ Ruanjian Sanjie law: traditional Chinese medicine theory, pointed out that the cancer as hard as stone, “Kennedy who cut the”, “those who loose the knot,” “In addition to the passenger who.” This method has been widely used in clinical. Combination with other therapies, can enhance the effect of eliminating carcinoma.
â‘¥ phlegm Qushi France: Many tumor is caused by phlegm cohesion, therefore, phlegm dampness in Chinese medicine treatment method in tumor occupies an important position, it will not only ease the symptoms, for some tumors can also be brought under control.
Chinese medicine treatment for breast cancer has always been the method is used within the rule, according to the principle of syndrome differentiation, mainly based on “dialectical seek cause, the trial due to Treating” is divided into qi stagnation, Chong and Ren disorders, stasis drug resistance , blood administering treatment failure, type 4, respectively.
(2) Differential Treatment of law:
â‘  liver Qi stagnation type:
Main symptoms: the impassioned injured, wish fail to materialize, qi stagnation, blood disorders caused by the body, organs dysfunction arising from breast lumps, pain, the two threatened to bulge, upset irritability, pulse string slip, thin yellow tongue coating or a thin white.
Governing law: Shugan qi, promoting blood circulation Sanjie.
Recipe: Angelica 9g, peony root 9g, Bupleurum 9g, orange leaves 9g, Angelica 6g, Qingpi 6g, Trichosanthes 30g, Fuling 9g, Atractylodes 9g.
Editor’s note: the breast is located Xiong Xie, to the liver through the cloth, liver failure Shuxie breast fullness feeling pain appeared to threaten the pain and uncomfortable symptoms of liver depression. The course of time into the blood stasis caused by qi stagnation, knot in the milk into blocks. Fang Bupleurum, Qingpi, orange leaf Shugan Qi Sanjie; angelica, peony root nourishing Rougan; Trichosanthes, Angelica swelling Sanjie pain; Poria, Atractylodes Lishi spleen Qi.
â‘¡ Chong and Ren disorder type:
Main symptoms: In addition to the above-mentioned symptoms of liver Qi stagnation, the both menstrual disorders, Yaotuisuanruan, five upset hot, pulse breakdown weakness, tongue red, moss little cracking.
Governing law: Shugan qi, nourishing the liver and kidney, conditioning Chong and Ren.
Recipe: Cyperus rotundus 10g, turmeric 10g, Fructus Toosendan 10g, white peony root 15g, orange leaves 10g, Chuan Xiong 10g, Chinese angelica 10g, Health Rehmannia the 15g, Ligustrum lucidum 10g, wolfberry fruit 15g, Health yam 15g, wild chrysanthemum 15g , Trichosanthes 30g.
Editor’s note: Liver depression of fire, burn-induced liver and kidney Yin Ye, Chong and Ren disorders. Fang angelica, Chuanxiong, Shude, white peony root conditioning blood; habitat, wolfberry fruit, Ligustrum lucidum Ziyin kidney; Cyperus rotundus, turmeric, Fructus Toosendan, orange leaf Shugan Qi; Health yam spleen; wild chrysanthemum, Trichosanthes detoxification Sanjie.
â‘¢ toxic Heat Accumulation Type:
Main symptoms: rapid increase of breast lumps, pain, is very ulceration and look at flowers.
Governing law: attack drug detoxification.
Recipe: Fern 9g, Solanum rattan 30g, Siphonostegia 9g, iron leaves 15g, hive 9g, snake slough 3g, dung beetle insect 9g, Maozhaocao 30g, Mountain Arrowhead 15g, ghost arrows feather 9g.
Editor’s note: Thermal drug Accumulation advised to attack drug detoxification. Fang Pteris grass, Solanum rattan, Siphonostegia, iron leaves Qingrejiedu; hive, snake slough, mantis insects, Ranunculus grass, mountain Arrowhead, ghost feather arrows huoxuehuayu detoxification.
â‘£ blood deficiency type:
Main symptoms: Breast fester If it persists, blood decay, burned by righteousness, but see the pale and anemia, weight loss fatigue, dry mouth, tongue dull red, yellow and white tongue fur, slippery pulse number.
Governing law: rousing, blood pairs of fill.
Recipe: Soil fried Baizhu 12g, Ginseng, Poria, Citrus, Shude, Chuanxiong, angelica, Fritillaria, Cyperus rotundus, white peony root all 6g, Campanulaceae, licorice the 3g.
Editor’s note: breast cancer in the late show is virtual evil disease found in the real situation, government should be rousing, qi nourishing. Turkish side fried Baizhu, ginseng, Poria, Rehmannia, Chuanxiong, angelica spleen Qi, blood and blood circulation; dried tangerine peel, Cyperus rotundus, Campanulaceae qi Sanjie; licorice to reconcile various drugs, rousing.
(3) The ancient medical side for example: the ancient Chinese literature, the treatment of breast cancer herbs a lot, there is within the extraterritorial rule Ogata, the following give a few examples for reference.
â‘  Health crab shells on a baking tile coke, Yan Mo, red wine, each serving 6g, in order to eliminate the degrees. Governance breast cancer early, hard tumor as big as beans.
â‘¡ Sichuan turmeric 10g, roses 10g, Qingpi, dried tangerine peel the 8g, orange leaves, red peony root, mountain Arrowhead, Jiangcan the 10g, Chinese angelica 15g, Trichosanthes 30g, decoction sub-service. Early indications of breast cancer, or breast cancer post-operative treatment.
Gas-flow drinks taste â‘¢ 16: Angelica, white peony root, ginseng, bellflower, Chuanxiong, Citrus aurantium, Magnolia, Angelica, Su Ye, wind, Lindera aggregata, betel nuts each 10g, Radix Astragali 20g, Guan Gui, wood-pass the 4g, licorice 6g, Jianfu. Treatment for breast cancer liver depression qi stagnation, blood deficiency were.
â‘£ Ji Zhi carp paste: live carp, fresh yam (peeled) of the equal parts, a total of pound drunk, such as musk little, painted the nucleus, it feels very itchy, do not scratch the move, 7 days a change. Governance Ruyan early. External application.
⑤ whip cream Rong: Hibiscus leaves, Eupatorium leaves, cork, Huangcen, berberine, rhubarb each equal parts, a total of inquiry into Ximo, heavy baskets, into borneol 6g, tune into the 20% with Vaseline ointment. Attending inflammatory breast cancer. In addition, the anti-cancer traditional Chinese medicine frequently used in the treatment of breast cancer are: Mountain Arrowhead, soil Fritillaria, Trichosanthes, orange leaves, dandelion, Loulu, leaving Yukiko, pangolins, days ambrette, Solanum nigrum, Qingpi, hibiscus flowers, Aescin a flower and so on.